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ObjectiveTo explore the syndrome and treatment rules of traditional Chinese medicine （TCM） in treating chronic obstructive pulmonary disease （COPD） based on the medical literature and cases with the help of TCM inheritance support system platform （V2.5）， thus providing new ideas for TCM to treat COPD. MethodThe medical cases of TCM treating COPD were retrieved from China national knowledge infrastructure （CNKI）， Wanfang Database， and VIP China Science and Technology Journal Database. The medical cases that met the inclusion literature were collected in a new Word document， and then input into the TCM inheritance support system platform （V2.5） after data standardization. With the help of the algorithm carried by this software， the frequency statistics of "symptoms， syndrome types of TCM， Chinese medicine， and meridians of Chinese medicine" in the included COPD medical cases were performed， and the correlation analysis of the "prescription rules" in the included medical cases was carried out， thus excavating the potential core drug pairs and new prescriptions for the treatment of COPD. ResultA total of 103 articles were included with 126 medical cases and 131 diagnoses and treatments. According to statistics， the common symptoms of COPD were cough， expectoration， chest tightness， and asthma， and the common TCM syndromes included phlegm-heat obstructing lung， phlegm and blood stasis blocking lung， and lung-spleen Qi deficiency. The common TCM treatment methods included clearing heat and resolving phlegm， banking up earth to generate metal， and descending adverse and relieving dyspnea， among which the high-frequency Chinese medicines for the treatment of COPD were Pinelliae Rhizoma， Armeniacae Semen Amarum， Ephedrae Herba， Citri Reticulatae Pericarpium， and so on. The commonly used drug pairs included Asari Radix et Rhizoma-Pinelliae Rhizoma， Pinelliae Rhizoma-Schisandrae Chinensis Fructus-Glycyrrhizae Radix et Rhizoma， etc. Twelve new prescriptions for the treatment of COPD were found. ConclusionTCM believes that COPD is a lung disease formed by external evil， phlegm， blood stasis， and other pathological factors， with cough， phlegm， and asthma as the main symptoms. The main syndromes of COPD are phlegm-heat obstructing lung， phlegm and blood stasis blocking lung， and lung-spleen qi deficiency. "Strengthening the upright and dispelling evil" is the basic principle of the treatment COPD. In clinical， TCM methods with dispelling phlegm and removing blood stasis， and tonifying lung， spleen， and kidney should be adopted to treat COPD.
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Objective:To establish a supportive and effective management mode of scientific research project application, promote the capacity building of scientific research in the hospital.Methods:Retrospective analysis was conducted on the national and provincial scientific research projects of Xinhua Hospital Affiliated to Shanghai Jiaotong University Medical School from 2010 to 2019, and the practical effect of " point to point" management mode of scientific research project application was evaluated.Results:The funding rate of Xinhua Hospital, especially national scientific research projects and provincial talents projects, was greatly improved by adoption of the multi-dimensional " point to point" management mode of scientific research project application. The number of national scientific research projects increased from 34 (26.02 million) in 2010 to 72 (51.0851 million) in 2019.The number of provincial talents projects increased from 5 (1.05 million) in 2010 to 26 (6.5 million) in 2019.Conclusions:The " point to point" management mode of scientific research project application plays an important role in promoting the overall funding rate. Enhancement of comprehensive capacity of hospital scientific research can be achieved by further improvement of this management mode, early initiation and arrangement of funding application depending on the " close partner" entity, emphasizing scientific research talents cultivation.
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The present study was designed to explore the possible neuroprotective role of protocatechuic acid (3,4-dihydroxybenzoic acid) against rotenone induced locomotor, oxidative and mitochondrial dysfunction in mice. We also wanted to evaluate its ability to prevent neuronal degeneration in rotenone intoxicated mice. MethodsThirty mice, Albino strain, between 20 – 25 g, were included in the study. Group 1 is control group. It received sunflower oil 0.1 mL subcutaneously for two weeks. Group 2 received rotenone (1 mg / Kg) S.C. Group 3 also received rotenone (1 mg / Kg / day) S.C. in sunflower oil alternatively and Protocatechuic acid 10 mg / Kg B.W. P.O. for 2 weeks. Group 4 and 5 received rotenone as same in group 2 and Protocatechuic acid (25 mg / Kg) and (50 mg / Kg) B.W. P.O. After the finish of trial, open field test, stride length measurement, catalepsy, forced swim test, sucrose preference test and elevated plus maze test were conducted. ResultsExposure to Rotenone in mice led to reduction in peripheral and central movements. Pre-treatment with protocatechuic acid prior to rotenone exposure was able to maintain the both motor and non-motor symptoms of PD. However, protocatechuic acid was effective in the maintenance of dopaminergic and nondopaminergic pathways. ConclusionsThis study strengthens the fact that the protocatechuic acid in rotenone-affected areas might offer neuroprotection.
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Objective@#To know the incidence of heat stroke and explore it's prediction model in Pudong New Area of Shanghai. @*Methods@#An epidemiological investigation was conducted on heat stroke cases in Pudong New Area of Shanghai from 2013 to 2017. Daily temperature data during this period were collected to explore it’s influence. @*Results@#246 heat stroke cases were reported and investigated, 70.3% (173/246) of them were male. 170 cases are severe heat stroke, accounting for 69.1%. 28 patients died, accounting for 11.4% of all cases of heat stroke, and 16.5% (28/170) of severe heat stroke cases. Thermoplegia (56.5%, 96/170) was the most popular type among severe heat stroke cases. Heat prostration, heat cramps and mixed type account for 17.1% (29/170) , 12.4% (21/170) and 14.0% (24/170) respectively. Scatter plot and linear regression demonstrated that there was a significant linear relation between number of high temperature days and number of heat stroke cases (P<0.01) . And the prediction model is: Predictive number of annual heat stroke cases=β×Number of annual high temperature days+Intercept. Leave-one-out cross validation result shows that the predictive number of annual heat stroke cases from 2013 to 2017 were 85.7%, 90.9%, 83.3%, 91.9 and 84.3% respectively. @*Conclusion@#There was a significant linear relation between number of high temperature days and number of heat stroke cases in Pudong New Area. The related work arrangement for heat stroke prevention could be well planed according to the prediction model.
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Pang Zanxiang was a famous ophthalmologist of Chinese medicine. Based on his family experience and combined with his clinical practice, he has written the book Clinical practice of ophthalmology in traditional Chinese medicine. In the book, the theory of stagnation of Qi and blood leading to disease was put forward, and radix stellariae was used most frequently in treating eye disease. From literature interview, we found that pang’s experience of radix stellariae in treating eye disease was its function of replenishing vital essence to improve eyesight.
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Objective To explore different management on malposition of PICC line.Methods 36 PICC line malposition clients,who went through pulling the catheter back,adjusting the position of the insertion limb were not successful,but by using the combination of the following 5 methods can successfully manage the malposition of PICC line:pulling the catheter 1cm back from the commencement point,withdrawing some length of catheter,Changing position,palpating clients' back,practising deep breathing,then X ray to confirm the catheter tip location,record the times and the successful rate.Results Among 36 clients,31 were managed successfully by the first time,3 Clients twice and 2 clients were not successful and had to remove inserted successfully at the basilica vein at the opposite arm.Overall,the successful rate is 94％.Conclusions The combination of the following 5 methods can successfully manage the malposition of PICC line:pulling the catheter 1 cm back from the commencement point,withdrawing some length of catheter,Changing position,palpating clients' back,practising deep breathing.
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Objective To explore the health education model of cerebral palsy rehabilitation.Methods Forty children with spastic cerebral palsy were screened and randomly divided into the therapy group and the control group.All the children received common health education,but parents of the therapy group were offered new standardized systematic health education whenever their children were in hospital or discharged from hospital by primary nurses.The Improved Ashworth Spasm Evaluation,GMFM evaluation and ADL evaluation were respectively performed in both the therapy and the control groups before the treatment and after six-month rehabilitation.Results There was no significant difference in the index score between both groups before the treatment.After six months,all the above indicators increased in both groups.And notably,significandy more increment was observed compared with the control group.Conclusions The new health education can further improve gross motor function and ADL of cerebral palsy children,which can be popularized and used as a new health education model for cerebral palsy rehabilitation.
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Fu-Zheng Pei-Ben therapy, as a major therapeutic principle, has become the main guiding thought of cancer therapy currently. Through the traditional Chinese medicine (TCM) history, Fu-Zheng Pei-Ben thera-py is one of the most important therapies . As early as the Spring and Autumn Period , the importance of vital qi has been recorded in the Huang-Di Nei-Jing. After that, TCM doctors have enriched the connotation and extension of the Fu-Zhe ng therapy . Until modern times , Professor Liu Jiaxiang applied Fu-Zhe ng therapy to the treatment of cancer . This paper explained the sources of Fu-Zhe ng cancer therapy through the analy-sis of its history in order to provide a reference to deepen the theoretical studies in the diagnosis and treat-ment of cancer in the future .
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Objective To develop a mental maturity test for adults.Methods On the basic of correlative theories,the structure of Adults Mental Maturity was established by using interview and exploratory factors analysis. The reliability and validity of this test were examined. Results Through exploratory factor analysis the test was of six factors self-insight, social cognition, emotion management, social contact style, adapting ability, loving ability. The reliability of test was 0.621～0.853, and the retest reliability was 0.431～0.831. Conclusion The test of mental maturity for adults is of better reliability and validity, and can be used in practice.
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Objective To strengthen the management of contaminated area of sterilization and supply center, increase the cleaning quality of instruments and control nosocomial infection. Methods We executed the following measures: paying attention to the decontamination work, changing concepts, refining regulations, establishing programmed decontamination process, specification of work, thinning pest responsibility, strengthening infection mangement of contaminated area, effect examination and training and checking. Results The bacteria removing rate reached 95.3%. Conclusions Refining management could result in perfect cleaning effect which was applicable in the management of contaminated area of sterilization and supply center.
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Objective To explore the new diabetes care model. Methods A new flow for diabetic outpatient to visit the doctor, a uniform system for diagnosis,treatment and follow-up,an electronic medical record system,and a long-term diabetes education which mainly delighted patients on "diabetic self-management" were established.(Results)The service quality from the medical staff were improved markedly.Database including the clinical data of 10 020 patients and 2 563 serum samples and DNA samples were built up.A set of diabetes care model that laid the foundation for clinical and research work was formed. Conclusion Long-term education for patients with diabetes mellitus constitues the basic and important part of diabetic care model.The application of computer in diabetic care is the effective means.It is necessary to establish a uniform scheme for diagnosis,treatment and follow-up for the patients,and the improvement of medical staff's professional making ensures the successful implementation of the model.The combination of clinical practice and research work propels the development of scientific management model for patients with diabetes mellitus.
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The present situation and problems in experiment teaching of analytical chemistry were explained,and innovation was explored and practiced in the faculty of laboratory medicine,including the opitimization of teaching contents,teaching methods and score system evaluation reformation.
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@#ObjectiveTo explore the mental problems of landless farmer for improving their mental health.MethodsThe questionnaire was used in a survey of 322 landless farmers in east and west China and the impacts of demographic and psychosocial factors on mental problems of landless farmers were also analyzed.ResultsThe landless farmers in China had little symptoms of mental problems, but the status of mental health for landless farmers in west China was worse that those in east China. The different mental symptoms of landless farmers were affected by demographic and psychosocial factors in different degrees.ConclusionThe study reveals that special attention and concern might be attached to the employment and the vocation training of landless farmers, especially to the landless farmers in west China.
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To play the best role of medical ethics education to people,medical ethics teaching forms and methods should be reformed with the specific conditions,the establishment of new student performance assessment appraisal mechanism should be mobilized,the enthusiasm and initiative of students studying medical ethics should be mobilized,and the effectiveness of teaching should be continually enhanced.
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This paper reviews author's own experience in medical ethics form the perspectives of academic conferences,literature editing,and scientific research,coming up with the conclusion that research in TCM ethics history is still far from satisfaction and calling for national support from certain policy making,fund sponsoring,and professionals cultivation.
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Object To observe the improving effects of BUSHEN YIZHI DECOCTION (BSYZD) on interspace explore learning and memory in rat model with Alzheimer's disease. Methods Eighty 15-month Wistar rats were induced by ip D -galactose for four weeks and injection of basal nucleus of Meynert with ibotenic acid (IBO) to make AD model, then randomly divided into AD model group, Hup-A treated group, BSYZD (high dose, 12 g/kg?d) treated group and BSYZD (low dose, 6 g/kg?d) treated group, and also normal aged and young groups. After treating for four weeks, Morris water maze was used to assess the improvement of rat interspace explore learning and memory. Results In the interspace explore experiment, the significant differences were observed between the model, Hup-A treated groups and normal aged, young groups (P0.05). Conclusion BSYZD possesses a certain preventive effects on interspace explore learning and memory in AD rat model.